Loss of Bright/ARID3a Function Promotes Developmental Plasticity
نویسندگان
چکیده
منابع مشابه
Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis
The effect of hypoxia on cellular metabolism is well documented in adult vertebrates, but information is entirely lacking for embryonic organisms. The effect of hypoxia on embryonic physiology is particularly interesting, as metabolic responses during development may have life-long consequences, due to developmental plasticity. To this end, we investigated the effects of chronic developmental h...
متن کاملDevelopmental plasticity
Developmental plasticity - the concept that adaptation to changing and unfavorable environmental conditions are possible but may come at the price of compromised health potentials - has evolutionary grounding as it facilitates survival but dissents with fundamental evolutionary principles in that it may advance the lesser fit. It is an important cornerstone of the Developmental Origins of Healt...
متن کاملDevelopmental plasticity
Early life constraints affecting phenotype in later life is a trend consistently observed across different species. Of particular relevance to evolutionary medicine are the effects of intra-uterine growth leading to diabetes, hypertension, cardiovascular disease and other age-related disorders. The broader question of conditions under which such developmental plasticity or predictive adaptive r...
متن کاملDevelopmental plasticity
Early life experiences can have profound and persistent effects on traits expressed throughout the life course, with consequences for later life behavior, disease risk, and mortality rates. The shaping of later life traits by early life environments, known as 'developmental plasticity', has been well-documented in humans and non-human animals, and has consequently captured the attention of both...
متن کاملLoss of Developmental Factors Impairs SCO Formation and Function
lifeline for supplying the brain with essential nutrients and growth factors throughout development and into adulthood. At the same time, the brain exercises constant control to ensure that the flow of CSF is homeostatic. CSF is secreted by the choroid plexus and moves rostrocaudally through the ventricles and into the subarachnoid space before being drained into the venous circulation (80). Fa...
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ژورنال
عنوان ژورنال: STEM CELLS
سال: 2010
ISSN: 1066-5099
DOI: 10.1002/stem.491